LOXL1 Antibody

Catalog Number:

37706

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: Q08397
NCBI Gene ID: 4016
Gene Accssion: NP_005567/Q08397

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide corresponding to residues near the C terminal of human lysyl oxidase-like 1

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total LOXL1 protein.

Applications:

WB

Background:

This gene encodes a member of the lysyl oxidase gene family. The prototypic member of the family is essential to the biogenesis of connective tissue, encoding an extracellular copper-dependent amine oxidase that catalyses the first step in the formation of crosslinks in collagens and elastin. A highly conserved amino acid sequence at the C-terminus end appears to be sufficient for amine oxidase activity, suggesting that each family member may retain this function. The N-terminus is poorly conserved and may impart additional roles in developmental regulation, senescence, tumor suppression, cell growth control, and chemotaxis to each member of the family.?

References:

appl_detail:

Western blotting: 1:200-1:1000

Datasheet PDF