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NFKB2 Antibody

Catalog Number:

37182
other_names: p52; p105; H2TF1; LYT10; LYT-10; NF-kB2

Amount:

100μg
calculated_mw:
host_species: Rabbit

Price:

$319

Swiss-Prot No:

Swiss-Prot#: Q00653
NCBI Gene ID: 4791
Gene Accssion: NP_001070962

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide corresponding to residues near the C terminal of human nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total NFKB2 protein.

Applications:

WB

Background:

This gene encodes one of the subunits of the transcription factor complex nuclear factor-kappa-B (NFkB). The NFkB transcription factor complex is expressed in numerous cell types and functions as a central activator of genes involved in inflammation and immune function. The NFkB complex can consist of different subunits that form both homo- or heterodimers which bind specific kappa-B elements in target genes. This gene encodes the p100 subunit that is processed into the active p52 subunit. This protein can function as both a transcriptional activator and repressor, depending on its dimer partner. Alternate splicing results in both coding and non-coding variants.?

References:

appl_detail:

Western blotting: 1:1000-1:5000

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