Product Datasheet
NFKB2 Antibody
Catalog Number: 37182
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: Q00653
NCBI Gene ID: 4791
Gene Accssion: NP_001070962
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic peptide corresponding to residues near the C terminal of human nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
- appl_detail:
- Western blotting: 1:1000-1:5000
- other_names:
- p52; p105; H2TF1; LYT10; LYT-10; NF-kB2
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total NFKB2 protein.
- Background:
- This gene encodes one of the subunits of the transcription factor complex nuclear factor-kappa-B (NFkB). The NFkB transcription factor complex is expressed in numerous cell types and functions as a central activator of genes involved in inflammation and immune function. The NFkB complex can consist of different subunits that form both homo- or heterodimers which bind specific kappa-B elements in target genes. This gene encodes the p100 subunit that is processed into the active p52 subunit. This protein can function as both a transcriptional activator and repressor, depending on its dimer partner. Alternate splicing results in both coding and non-coding variants.?
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