MUC5B Antibody

Catalog Number:

37171

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: Q9HC84
NCBI Gene ID: 727897
Gene Accssion: NP_002449

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide corresponding to residues near the C terminal of human mucin 5B, oligomeric mucus/gel-forming

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total MUC5B protein.

Applications:

IHC

Background:

This gene encodes a member of the mucin family of proteins, which are highly glycosylated macromolecular components of mucus secretions. This family member is the major gel-forming mucin in mucus. It is a major contributor to the lubricating and viscoelastic properties of whole saliva, normal lung mucus and cervical mucus. This gene has been found to be up-regulated in some human diseases, including sinus mucosa of chronic rhinosinusitis (CRS), CRS with nasal polyposis, chronic obstructive pulmonary disease (COPD) and H. pylori-associated gastric disease, and it may be involved in the pathogenesis of these diseases.

References:

appl_detail:

Immunohistochemistry: 1:25-1:100

Datasheet PDF