Product Datasheet
MUC5B Antibody
Catalog Number: 37171
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: Q9HC84
NCBI Gene ID: 727897
Gene Accssion: NP_002449
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic peptide corresponding to residues near the C terminal of human mucin 5B, oligomeric mucus/gel-forming
- appl_detail:
- Immunohistochemistry: 1:25-1:100
- other_names:
- MG1; MUC5; MUC9; MUC-5B
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total MUC5B protein.
- Background:
- This gene encodes a member of the mucin family of proteins, which are highly glycosylated macromolecular components of mucus secretions. This family member is the major gel-forming mucin in mucus. It is a major contributor to the lubricating and viscoelastic properties of whole saliva, normal lung mucus and cervical mucus. This gene has been found to be up-regulated in some human diseases, including sinus mucosa of chronic rhinosinusitis (CRS), CRS with nasal polyposis, chronic obstructive pulmonary disease (COPD) and H. pylori-associated gastric disease, and it may be involved in the pathogenesis of these diseases.
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