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MAP3K2 Antibody

Catalog Number:

37134
other_names: MEKK2; MEKK2B

Amount:

100μg
calculated_mw:
host_species: Rabbit

Price:

$319

Swiss-Prot No:

Swiss-Prot#: Q9Y2U5
NCBI Gene ID: 10746
Gene Accssion: NP_006600

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide corresponding to a region derived from internal residues of human mitogen-activated protein kinase kinase kinase 2

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total MAP3K2 protein.

Applications:

IHC

Background:

The protein encoded by this gene is a member of serine/threonine protein kinase family. This kinase preferentially activates other kinases involved in the MAP kinase signaling pathway. This kinase has been shown to directly phosphorylate and activate Ikappa B kinases, and thus plays a role in NF-kappa B signaling pathway. This kinase has also been found to bind and activate protein kinase C-related kinase 2, which suggests its involvement in a regulated signaling process.?

References:

appl_detail:

Immunohistochemistry: 1:25-1:100

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