Product Datasheet
MAP3K2 Antibody
Catalog Number: 37134
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: Q9Y2U5
NCBI Gene ID: 10746
Gene Accssion: NP_006600
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic peptide corresponding to a region derived from internal residues of human mitogen-activated protein kinase kinase kinase 2
- appl_detail:
- Immunohistochemistry: 1:25-1:100
- other_names:
- MEKK2; MEKK2B
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total MAP3K2 protein.
- Background:
- The protein encoded by this gene is a member of serine/threonine protein kinase family. This kinase preferentially activates other kinases involved in the MAP kinase signaling pathway. This kinase has been shown to directly phosphorylate and activate Ikappa B kinases, and thus plays a role in NF-kappa B signaling pathway. This kinase has also been found to bind and activate protein kinase C-related kinase 2, which suggests its involvement in a regulated signaling process.?
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