LIN28A Antibody

Catalog Number:

37118

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: Q9H9Z2
NCBI Gene ID: 79727
Gene Accssion: NP_078950

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide corresponding to residues near the N terminal of human lin-28 homolog A (C. elegans)

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total LIN28A protein.

Applications:

IHC

Background:

LIN-28 is a highly conserved, RNA-binding, cytoplasmic protein. It consists of a cold shock domain and retroviral-type (CCHC) zinc finger motifs that were first identified in Caenorhabditis elegans. LIN-28 controls the timing of events during embryonic development and is readily expressed in embryos, embryonic stem cells and embryonal carcinoma cells. The presence of LIN-28 persists in some adult tissues including cardiac and skeletal muscle. In differentiating myoblasts, LIN-28 increases protein synthesis efficiency and binds to the growth and differentiation factor IGF-II.

References:

appl_detail:

Immunohistochemistry: 1:25-1:100

Datasheet PDF