Product Datasheet  
LIN28A Antibody  
Catalog Number: 37118  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species:  
  • Rabbit
  • Amount:  
  • 100μgμg
  • Swiss-Prot No.:  
  • Swiss-Prot#: Q9H9Z2
    NCBI Gene ID: 79727
    Gene Accssion: NP_078950
  • Form of Antibody:  
  • Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
  • Storage:  
  • Store at -20˚C
  • Immunogen:  
  • Synthetic peptide corresponding to residues near the N terminal of human lin-28 homolog A (C. elegans)
  • reactivity:  
  • Hu Ms
  • appl_detail:  
  • Immunohistochemistry: 1:25-1:100
  • other_names:  
  • CSDD1; LIN28; LIN-28; ZCCHC1; lin-28A
  • Purification:  
  • Antigen affinity purification.
  • Specificity:  
  • The antibody detects endogenous levels of total LIN28A protein.
  • Applications:  
  • IHC
  • Background:  
  • LIN-28 is a highly conserved, RNA-binding, cytoplasmic protein. It consists of a cold shock domain and retroviral-type (CCHC) zinc finger motifs that were first identified in Caenorhabditis elegans. LIN-28 controls the timing of events during embryonic development and is readily expressed in embryos, embryonic stem cells and embryonal carcinoma cells. The presence of LIN-28 persists in some adult tissues including cardiac and skeletal muscle. In differentiating myoblasts, LIN-28 increases protein synthesis efficiency and binds to the growth and differentiation factor IGF-II.



 
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