TSC2 Antibody

Catalog Number:

37108

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: P49815
NCBI Gene ID: 7249
Gene Accssion: NP_000539

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide corresponding to residues near the C terminal of human tuberous sclerosis 2

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total TSC2 protein.

Applications:

IHC

Background:

Mutations in this gene lead to tuberous sclerosis complex. Its gene product is believed to be a tumor suppressor and is able to stimulate specific GTPases. The protein associates with hamartin in a cytosolic complex, possibly acting as a chaperone for hamartin. Alternative splicing results in multiple transcript variants encoding different isoforms.

References:

appl_detail:

Immunohistochemistry: 1:15-1:50

Datasheet PDF