Product Datasheet  
TSC2 Antibody  
Catalog Number: 37108  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot#: P49815
    NCBI Gene ID: 7249
    Gene Accssion: NP_000539
  • Form of Antibody：  
  • Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • Synthetic peptide corresponding to residues near the C terminal of human tuberous sclerosis 2
  • reactivity：  
  • Hu
  • appl_detail：  
  • Immunohistochemistry: 1:15-1:50
  • other_names：  
  • LAM; TSC4
  • Purification：  
  • Antigen affinity purification.
  • Specificity：  
  • The antibody detects endogenous levels of total TSC2 protein.
  • Applications：  
  • IHC
  • Background：  
  • Mutations in this gene lead to tuberous sclerosis complex. Its gene product is believed to be a tumor suppressor and is able to stimulate specific GTPases. The protein associates with hamartin in a cytosolic complex, possibly acting as a chaperone for hamartin. Alternative splicing results in multiple transcript variants encoding different isoforms.



 
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