AGRP Antibody

Catalog Number:

37093

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: O00253
NCBI Gene ID: 181
Gene Accssion: NP_001129

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide corresponding to a region derived from internal residues of human agouti related protein homolog (mouse)

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total AGRP protein.

Applications:

IHC

Background:

This gene encodes an antagonist of the melanocortin-3 and melanocortin-4 receptor. It appears to regulate hypothalamic control of feeding behavior via melanocortin receptor and/or intracellular calcium regulation, and thus plays a role in weight homeostasis. Mutations in this gene have been associated with late on-set obesity.

References:

appl_detail:

Immunohistochemistry: 1:25-1:100

Datasheet PDF