Product Datasheet  
AGRP Antibody  
Catalog Number: 37093  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species:  
  • Rabbit
  • Amount:  
  • 100μgμg
  • Swiss-Prot No.:  
  • Swiss-Prot#: O00253
    NCBI Gene ID: 181
    Gene Accssion: NP_001129
  • Form of Antibody:  
  • Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
  • Storage:  
  • Store at -20˚C
  • Immunogen:  
  • Synthetic peptide corresponding to a region derived from internal residues of human agouti related protein homolog (mouse)
  • reactivity:  
  • Hu
  • appl_detail:  
  • Immunohistochemistry: 1:25-1:100
  • other_names:  
  • ART; AGRT; ASIP2
  • Purification:  
  • Antigen affinity purification.
  • Specificity:  
  • The antibody detects endogenous levels of total AGRP protein.
  • Applications:  
  • IHC
  • Background:  
  • This gene encodes an antagonist of the melanocortin-3 and melanocortin-4 receptor. It appears to regulate hypothalamic control of feeding behavior via melanocortin receptor and/or intracellular calcium regulation, and thus plays a role in weight homeostasis. Mutations in this gene have been associated with late on-set obesity.



 
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