Product Datasheet
AGRP Antibody
Catalog Number: 37093
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: O00253
NCBI Gene ID: 181
Gene Accssion: NP_001129
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic peptide corresponding to a region derived from internal residues of human agouti related protein homolog (mouse)
- appl_detail:
- Immunohistochemistry: 1:25-1:100
- other_names:
- ART; AGRT; ASIP2
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total AGRP protein.
- Background:
- This gene encodes an antagonist of the melanocortin-3 and melanocortin-4 receptor. It appears to regulate hypothalamic control of feeding behavior via melanocortin receptor and/or intracellular calcium regulation, and thus plays a role in weight homeostasis. Mutations in this gene have been associated with late on-set obesity.
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