ADAR Antibody

Catalog Number:

37084

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: P55265
NCBI Gene ID: 103
Gene Accssion: NP_001102

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide corresponding to a region derived from internal residues of human adenosine deaminase, RNA-specific

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total ADAR protein.

Applications:

IHC

Background:

This gene encodes the enzyme responsible for RNA editing by site-specific deamination of adenosines. This enzyme destabilizes double-stranded RNA through conversion of adenosine to inosine. Mutations in this gene have been associated with dyschromatosis symmetrica hereditaria. Alternative splicing results in multiple transcript variants.

References:

appl_detail:

Immunohistochemistry: 1:50-1:200

Datasheet PDF