Product Datasheet
ADAR Antibody
Catalog Number: 37084
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: P55265
NCBI Gene ID: 103
Gene Accssion: NP_001102
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic peptide corresponding to a region derived from internal residues of human adenosine deaminase, RNA-specific
- appl_detail:
- Immunohistochemistry: 1:50-1:200
- other_names:
- DSH; AGS6; G1P1; IFI4; P136; ADAR1; DRADA; DSRAD; IFI-4; K88DSRBP
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total ADAR protein.
- Background:
- This gene encodes the enzyme responsible for RNA editing by site-specific deamination of adenosines. This enzyme destabilizes double-stranded RNA through conversion of adenosine to inosine. Mutations in this gene have been associated with dyschromatosis symmetrica hereditaria. Alternative splicing results in multiple transcript variants.
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