NFATC2 Antibody

Catalog Number:

37065

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: B5B2P4
NCBI Gene ID: 4773
Gene Accssion: NP_775114.1

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide corresponding to residues near the N terminal of human nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total NFATC2 protein.

Applications:

IHC

Background:

This gene is a member of the nuclear factor of activated T cells (NFAT) family. The product of this gene is a DNA-binding protein with a REL-homology region (RHR) and an NFAT-homology region (NHR). This protein is present in the cytosol and only translocates to the nucleus upon T cell receptor (TCR) stimulation, where it becomes a member of the nuclear factors of activated T cells transcription complex. This complex plays a central role in inducing gene transcription during the immune response. Alternate transcriptional splice variants encoding different isoforms have been characterized.

References:

appl_detail:

Immunohistochemistry: 1:25-1:100

Datasheet PDF