Product Datasheet
NFATC2 Antibody
Catalog Number: 37065
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: B5B2P4
NCBI Gene ID: 4773
Gene Accssion: NP_775114.1
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic peptide corresponding to residues near the N terminal of human nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2
- appl_detail:
- Immunohistochemistry: 1:25-1:100
- other_names:
- NFAT1; NFATP
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total NFATC2 protein.
- Background:
- This gene is a member of the nuclear factor of activated T cells (NFAT) family. The product of this gene is a DNA-binding protein with a REL-homology region (RHR) and an NFAT-homology region (NHR). This protein is present in the cytosol and only translocates to the nucleus upon T cell receptor (TCR) stimulation, where it becomes a member of the nuclear factors of activated T cells transcription complex. This complex plays a central role in inducing gene transcription during the immune response. Alternate transcriptional splice variants encoding different isoforms have been characterized.
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