NTRK1 Antibody

Catalog Number:

37056

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: P04629
NCBI Gene ID: 4914
Gene Accssion: NP_002520.2

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide corresponding to residues near the C terminal of human neurotrophic tyrosine kinase, receptor, type 1

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total NTRK1 protein.

Applications:

IHC

Background:

This gene encodes a member of the neurotrophic tyrosine kinase receptor (NTKR) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. The presence of this kinase leads to cell differentiation and may play a role in specifying sensory neuron subtypes. Mutations in this gene have been associated with congenital insensitivity to pain, anhidrosis, self-mutilating behavior, mental retardation and cancer. Alternate transcriptional splice variants of this gene have been found, but only three have been characterized to date.

References:

appl_detail:

Immunohistochemistry: 1:100-1:300

Datasheet PDF