Product Datasheet  
NTRK1 Antibody  
Catalog Number: 37056  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot#: P04629
    NCBI Gene ID: 4914
    Gene Accssion: NP_002520.2
  • Form of Antibody：  
  • Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • Synthetic peptide corresponding to residues near the C terminal of human neurotrophic tyrosine kinase, receptor, type 1
  • reactivity：  
  • Hu
  • appl_detail：  
  • Immunohistochemistry: 1:100-1:300
  • other_names：  
  • MTC; TRK; TRK1; TRKA; Trk-A; p140-TrkA
  • Purification：  
  • Antigen affinity purification.
  • Specificity：  
  • The antibody detects endogenous levels of total NTRK1 protein.
  • Applications：  
  • IHC
  • Background：  
  • This gene encodes a member of the neurotrophic tyrosine kinase receptor (NTKR) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. The presence of this kinase leads to cell differentiation and may play a role in specifying sensory neuron subtypes. Mutations in this gene have been associated with congenital insensitivity to pain, anhidrosis, self-mutilating behavior, mental retardation and cancer. Alternate transcriptional splice variants of this gene have been found, but only three have been characterized to date.



 
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