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HNF1A Antibody

Catalog Number:

37049
other_names: HNF1; LFB1; TCF1; MODY3; TCF-1; HNF-1A; IDDM20

Amount:

100μg
calculated_mw:
host_species: Rabbit

Price:

$319

Swiss-Prot No:

Swiss-Prot#: P20823
NCBI Gene ID: 6927
Gene Accssion: NP_000536

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide corresponding to a region derived from internal residues of human HNF1 homeobox A

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total HNF1A protein.

Applications:

WB

Background:

The protein encoded by this gene is a transcription factor required for the expression of several liver-specific genes. The encoded protein functions as a homodimer and binds to the inverted palindrome 5'-GTTAATNATTAAC-3'. Defects in this gene are a cause of maturity onset diabetes of the young type 3 (MODY3) and also can result in the appearance of hepatic adenomas.

References:

appl_detail:

Western blotting: 1:500-1:2000

Datasheet PDF

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