Product Datasheet
HNF1A Antibody
Catalog Number: 37049
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: P20823
NCBI Gene ID: 6927
Gene Accssion: NP_000536
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic peptide corresponding to a region derived from internal residues of human HNF1 homeobox A
- appl_detail:
- Western blotting: 1:500-1:2000
- other_names:
- HNF1; LFB1; TCF1; MODY3; TCF-1; HNF-1A; IDDM20
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total HNF1A protein.
- Background:
- The protein encoded by this gene is a transcription factor required for the expression of several liver-specific genes. The encoded protein functions as a homodimer and binds to the inverted palindrome 5'-GTTAATNATTAAC-3'. Defects in this gene are a cause of maturity onset diabetes of the young type 3 (MODY3) and also can result in the appearance of hepatic adenomas.
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