ABCC3 Antibody

Catalog Number:

36982

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: O15438
NCBI Gene ID: 8714
Gene Accssion: NP_003777

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide corresponding to a region derived from internal residues of human ATP-binding cassette, sub-family C (CFTR/MRP), member 3

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total ABCC3 protein.

Applications:

IHC

Background:

The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. The specific function of this protein has not yet been determined; however, this protein may play a role in the transport of biliary and intestinal excretion of organic anions. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized. [

References:

appl_detail:

Immunohistochemistry: 1:15-1:50

Datasheet PDF