Product Datasheet
ABCC3 Antibody
Catalog Number: 36982
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: O15438
NCBI Gene ID: 8714
Gene Accssion: NP_003777
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic peptide corresponding to a region derived from internal residues of human ATP-binding cassette, sub-family C (CFTR/MRP), member 3
- appl_detail:
- Immunohistochemistry: 1:15-1:50
- other_names:
- MLP2; MRP3; ABC31; MOAT-D; cMOAT2; EST90757
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total ABCC3 protein.
- Background:
- The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. The specific function of this protein has not yet been determined; however, this protein may play a role in the transport of biliary and intestinal excretion of organic anions. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized. [
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