ITGAX Antibody

Catalog Number:

36961

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: P20702
NCBI Gene ID: 3687
Gene Accssion: NP_000878

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide corresponding to residues near the C terminal of human integrin, alpha X (complement component 3 receptor 4 subunit)

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total ITGAX protein.

Applications:

IHC

Background:

This gene encodes the integrin alpha X chain protein. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This protein combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as inactivated-C3b (iC3b) receptor 4 (CR4). The alpha X beta 2 complex seems to overlap the properties of the alpha M beta 2 integrin in the adherence of neutrophils and monocytes to stimulated endothelium cells, and in the phagocytosis of complement coated particles.

References:

appl_detail:

Immunohistochemistry: 1:15-1:50

Datasheet PDF