Product Datasheet
ITGAX Antibody
Catalog Number: 36961
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: P20702
NCBI Gene ID: 3687
Gene Accssion: NP_000878
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic peptide corresponding to residues near the C terminal of human integrin, alpha X (complement component 3 receptor 4 subunit)
- appl_detail:
- Immunohistochemistry: 1:15-1:50
- other_names:
- CD11C; SLEB6
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total ITGAX protein.
- Background:
- This gene encodes the integrin alpha X chain protein. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This protein combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as inactivated-C3b (iC3b) receptor 4 (CR4). The alpha X beta 2 complex seems to overlap the properties of the alpha M beta 2 integrin in the adherence of neutrophils and monocytes to stimulated endothelium cells, and in the phagocytosis of complement coated particles.
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