LRPPRC Antibody

Catalog Number:

36960

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: P42704
NCBI Gene ID: 10128
Gene Accssion: NP_573566

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide corresponding to a region derived from internal residues of human leucine-rich pentatricopeptide repeat containing

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total LRPPRC protein.

Applications:

IHC

Background:

This gene encodes a leucine-rich protein that has multiple pentatricopeptide repeats (PPR). The precise role of this protein is unknown but studies suggest it may play a role in cytoskeletal organization, vesicular transport, or in transcriptional regulation of both nuclear and mitochondrial genes. The protein localizes primarily to mitochondria and is predicted to have an N-terminal mitochondrial targeting sequence. Mutations in this gene are associated with the French-Canadian type of Leigh syndrome.

References:

appl_detail:

Immunohistochemistry: 1:15-1:50

Datasheet PDF