Product Datasheet
LRPPRC Antibody
Catalog Number: 36960
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: P42704
NCBI Gene ID: 10128
Gene Accssion: NP_573566
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic peptide corresponding to a region derived from internal residues of human leucine-rich pentatricopeptide repeat containing
- appl_detail:
- Immunohistochemistry: 1:15-1:50
- other_names:
- LSFC; GP130; LRP130; CLONE-23970
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total LRPPRC protein.
- Background:
- This gene encodes a leucine-rich protein that has multiple pentatricopeptide repeats (PPR). The precise role of this protein is unknown but studies suggest it may play a role in cytoskeletal organization, vesicular transport, or in transcriptional regulation of both nuclear and mitochondrial genes. The protein localizes primarily to mitochondria and is predicted to have an N-terminal mitochondrial targeting sequence. Mutations in this gene are associated with the French-Canadian type of Leigh syndrome.
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