ADRBK1 Antibody

Catalog Number:

36916

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: P25098
NCBI Gene ID: 156
Gene Accssion: NP_001610

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide corresponding to a region derived from internal residues of human adrenergic, beta, receptor kinase 1

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total ADRBK1 protein.

Applications:

IHC

Background:

The product of this gene phosphorylates the beta-2-adrenergic receptor and appears to mediate agonist-specific desensitization observed at high agonist concentrations. This protein is an ubiquitous cytosolic enzyme that specifically phosphorylates the activated form of the beta-adrenergic and related G-protein-coupled receptors. Abnormal coupling of beta-adrenergic receptor to G protein is involved in the pathogenesis of the failing heart.

References:

appl_detail:

Immunohistochemistry: 1:100-1:300

Datasheet PDF