SUMO2/SUMO3/SUMO4 Antibody

Catalog Number:

36877

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: P61956
NCBI Gene ID: 6613
Gene Accssion: NP_008868/NP_008867/NP_001002255

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide corresponding to a region derived from internal residues of human SMT3 suppressor of mif two 3 homolog 2/3/4 (S. cerevisiae)

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total SUMO2/SUMO3/SUMO4 protein.

Applications:

WB IHC

Background:

This gene encodes a protein that is a member of the SUMO (small ubiquitin-like modifier) protein family. It functions in a manner similar to ubiquitin in that it is bound to target proteins as part of a post-translational modification system. However, unlike ubiquitin which targets proteins for degradation, this protein is involved in a variety of cellular processes, such as nuclear transport, transcriptional regulation, apoptosis, and protein stability. It is not active until the last two amino acids of the carboxy-terminus have been cleaved off. Numerous pseudogenes have been reported for this gene. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

References:

appl_detail:

Western blotting: 1:500-1:2000
Immunohistochemistry: 1:100-1:300

Datasheet PDF