Product Datasheet  
SUMO2/SUMO3/SUMO4 Antibody  
Catalog Number: 36877  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot#: P61956
    NCBI Gene ID: 6613
    Gene Accssion: NP_008868/NP_008867/NP_001002255
  • Form of Antibody：  
  • Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • Synthetic peptide corresponding to a region derived from internal residues of human SMT3 suppressor of mif two 3 homolog 2/3/4 (S. cerevisiae)
  • reactivity：  
  • Hu Ms Rt
  • appl_detail：  
  • Western blotting: 1:500-1:2000
    Immunohistochemistry: 1:100-1:300
  • other_names：  
  • SMT3A; Smt3B; SMT3H1; SUMO-3; HSMT3; SMT3B; SUMO3; Smt3A; SMT3H2; IDDM5; SMT3H4; SUMO-4; dJ281H8.4
  • Purification：  
  • Antigen affinity purification.
  • Specificity：  
  • The antibody detects endogenous levels of total SUMO2/SUMO3/SUMO4 protein.
  • Applications：  
  • WB IHC
  • Background：  
  • This gene encodes a protein that is a member of the SUMO (small ubiquitin-like modifier) protein family. It functions in a manner similar to ubiquitin in that it is bound to target proteins as part of a post-translational modification system. However, unlike ubiquitin which targets proteins for degradation, this protein is involved in a variety of cellular processes, such as nuclear transport, transcriptional regulation, apoptosis, and protein stability. It is not active until the last two amino acids of the carboxy-terminus have been cleaved off. Numerous pseudogenes have been reported for this gene. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.



 
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