EDAR Antibody

Catalog Number:

36834

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: Q9UNE0
NCBI Gene ID: 10913
Gene Accssion: NP_071731

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide corresponding to a region derived from internal residues of human Ectodysplasin-A receptor

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total EDAR protein.

Applications:

IHC

Background:

This gene encodes a member of the tumor necrosis factor receptor family. The encoded transmembrane protein is a receptor for the soluble ligand ectodysplasin A, and can activate the nuclear factor-kappaB, JNK, and caspase-independent cell death pathways. It is required for the development of hair, teeth, and other ectodermal derivatives. Mutations in this gene result in autosomal dominant and recessive forms of hypohidrotic ectodermal dysplasia.

References:

appl_detail:

Immunohistochemistry: 1:10-1:50

Datasheet PDF