Product Datasheet
EDAR Antibody
Catalog Number: 36834
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: Q9UNE0
NCBI Gene ID: 10913
Gene Accssion: NP_071731
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic peptide corresponding to a region derived from internal residues of human Ectodysplasin-A receptor
- appl_detail:
- Immunohistochemistry: 1:10-1:50
- other_names:
- DL; ED3; ED5; ED1R; EDA3; HRM1; EDA1R; EDA-A1R
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total EDAR protein.
- Background:
- This gene encodes a member of the tumor necrosis factor receptor family. The encoded transmembrane protein is a receptor for the soluble ligand ectodysplasin A, and can activate the nuclear factor-kappaB, JNK, and caspase-independent cell death pathways. It is required for the development of hair, teeth, and other ectodermal derivatives. Mutations in this gene result in autosomal dominant and recessive forms of hypohidrotic ectodermal dysplasia.
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