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TRDMT1 Antibody

Catalog Number:

36827
other_names: DMNT2; DNMT2; PUMET; RNMT1; MHSAIIP

Amount:

100μg
calculated_mw:
host_species: Rabbit

Price:

$319

Swiss-Prot No:

Swiss-Prot#: O14717
NCBI Gene ID: 1787
Gene Accssion: NP_004403

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide corresponding to a region derived from internal residues of human tRNA aspartic acid methyltransferase 1

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total TRDMT1 protein.

Applications:

IHC

Background:

This gene encodes a protein responsible for the methylation of aspartic acid transfer RNA, specifically at the cytosine-38 residue in the anticodon loop. This enzyme also possesses residual DNA-(cytosine-C5) methyltransferase activity. While similar in sequence and structure to DNA cytosine methyltransferases, this gene is distinct and highly conserved in its function among taxa.

References:

appl_detail:

Immunohistochemistry: 1:50-1:200

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