Product Datasheet
TRDMT1 Antibody
Catalog Number: 36827
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: O14717
NCBI Gene ID: 1787
Gene Accssion: NP_004403
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic peptide corresponding to a region derived from internal residues of human tRNA aspartic acid methyltransferase 1
- appl_detail:
- Immunohistochemistry: 1:50-1:200
- other_names:
- DMNT2; DNMT2; PUMET; RNMT1; MHSAIIP
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total TRDMT1 protein.
- Background:
- This gene encodes a protein responsible for the methylation of aspartic acid transfer RNA, specifically at the cytosine-38 residue in the anticodon loop. This enzyme also possesses residual DNA-(cytosine-C5) methyltransferase activity. While similar in sequence and structure to DNA cytosine methyltransferases, this gene is distinct and highly conserved in its function among taxa.
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