CCNT1 Antibody

Catalog Number:

36822

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: O60563
NCBI Gene ID: 904
Gene Accssion: NP_001231

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide corresponding to a region derived from internal residues of human cyclin T1

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total CCNT1 protein.

Applications:

IHC

Background:

This gene encodes a member of the highly conserved cyclin C subfamily. The encoded protein tightly associates with cyclin-dependent kinase 9, and is a major subunit of positive transcription elongation factor b (p-TEFb). In humans, there are multiple forms of positive transcription elongation factor b, which may include one of several different cyclins along with cyclin-dependent kinase 9. The complex containing the encoded cyclin and cyclin-dependent kinase 9 acts as a cofactor of human immunodeficiency virus type 1 (HIV-1) Tat protein, and is both necessary and sufficient for full activation of viral transcription.?

References:

appl_detail:

Immunohistochemistry: 1:25-1:100

Datasheet PDF