Product Datasheet
CCNT1 Antibody
Catalog Number: 36822
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: O60563
NCBI Gene ID: 904
Gene Accssion: NP_001231
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic peptide corresponding to a region derived from internal residues of human cyclin T1
- appl_detail:
- Immunohistochemistry: 1:25-1:100
- other_names:
- CCNT; CYCT1; HIVE1
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total CCNT1 protein.
- Background:
- This gene encodes a member of the highly conserved cyclin C subfamily. The encoded protein tightly associates with cyclin-dependent kinase 9, and is a major subunit of positive transcription elongation factor b (p-TEFb). In humans, there are multiple forms of positive transcription elongation factor b, which may include one of several different cyclins along with cyclin-dependent kinase 9. The complex containing the encoded cyclin and cyclin-dependent kinase 9 acts as a cofactor of human immunodeficiency virus type 1 (HIV-1) Tat protein, and is both necessary and sufficient for full activation of viral transcription.?
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