CCNB2 Antibody

Catalog Number:

36818

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: O95067
NCBI Gene ID: 9133
Gene Accssion: NP_004692

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide corresponding to a region derived from internal residues of human cyclin B2

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total CCNB2 protein.

Applications:

IHC

Background:

Cyclin B2 is a member of the cyclin family, specifically the B-type cyclins. The B-type cyclins, B1 and B2, associate with p34cdc2 and are essential components of the cell cycle regulatory machinery. B1 and B2 differ in their subcellular localization. Cyclin B1 co-localizes with microtubules, whereas cyclin B2 is primarily associated with the Golgi region. Cyclin B2 also binds to transforming growth factor beta RII and thus cyclin B2/cdc2 may play a key role in transforming growth factor beta-mediated cell cycle control.

References:

appl_detail:

Immunohistochemistry: 1:10-1:50

Datasheet PDF