Product Datasheet
CCNB2 Antibody
Catalog Number: 36818
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: O95067
NCBI Gene ID: 9133
Gene Accssion: NP_004692
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic peptide corresponding to a region derived from internal residues of human cyclin B2
- appl_detail:
- Immunohistochemistry: 1:10-1:50
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total CCNB2 protein.
- Background:
- Cyclin B2 is a member of the cyclin family, specifically the B-type cyclins. The B-type cyclins, B1 and B2, associate with p34cdc2 and are essential components of the cell cycle regulatory machinery. B1 and B2 differ in their subcellular localization. Cyclin B1 co-localizes with microtubules, whereas cyclin B2 is primarily associated with the Golgi region. Cyclin B2 also binds to transforming growth factor beta RII and thus cyclin B2/cdc2 may play a key role in transforming growth factor beta-mediated cell cycle control.
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