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CX3CR1 Antibody

Catalog Number:

36817
other_names: V28; CCRL1; GPR13; CMKDR1; GPRV28; CMKBRL1

Amount:

100μg
calculated_mw:
host_species: Rabbit

Price:

$319

Swiss-Prot No:

Swiss-Prot#: P49238
NCBI Gene ID: 1524
Gene Accssion: NP_001328

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide corresponding to residues near the N terminal of human chemokine (C-X3-C motif) receptor 1

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total CX3CR1 protein.

Applications:

WB

Background:

Fractalkine is a transmembrane protein and chemokine involved in the adhesion and migration of leukocytes. The protein encoded by this gene is a receptor for fractalkine. The encoded protein also is a coreceptor for HIV-1, and some variations in this gene lead to increased susceptibility to HIV-1 infection and rapid progression to AIDS. Four transcript variants encoding two different isoforms have been found for this gene.

References:

appl_detail:

Western blotting: 1:500-1:2000

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