Product Datasheet
CX3CR1 Antibody
Catalog Number: 36817
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: P49238
NCBI Gene ID: 1524
Gene Accssion: NP_001328
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic peptide corresponding to residues near the N terminal of human chemokine (C-X3-C motif) receptor 1
- appl_detail:
- Western blotting: 1:500-1:2000
- other_names:
- V28; CCRL1; GPR13; CMKDR1; GPRV28; CMKBRL1
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total CX3CR1 protein.
- Background:
- Fractalkine is a transmembrane protein and chemokine involved in the adhesion and migration of leukocytes. The protein encoded by this gene is a receptor for fractalkine. The encoded protein also is a coreceptor for HIV-1, and some variations in this gene lead to increased susceptibility to HIV-1 infection and rapid progression to AIDS. Four transcript variants encoding two different isoforms have been found for this gene.
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