KMT2D Antibody

Catalog Number:

37139

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: Q9UMN6
NCBI Gene ID: 9757
Gene Accssion: NP_003473

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide corresponding to residues near the N terminal of human lysine (K)-specific methyltransferase 2D

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total KMT2D protein.

Applications:

IHC

Background:

The protein encoded by this gene is a histone methyltransferase that methylates the Lys-4 position of histone H3. The encoded protein is part of a large protein complex called ASCOM, which has been shown to be a transcriptional regulator of the beta-globin and estrogen receptor genes. Mutations in this gene have been shown to be a cause of Kabuki syndrome.

References:

appl_detail:

Immunohistochemistry: 1:50-1:200

Datasheet PDF