Product Datasheet
KMT2D Antibody
Catalog Number: 37139
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: Q9UMN6
NCBI Gene ID: 9757
Gene Accssion: NP_003473
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic peptide corresponding to residues near the N terminal of human lysine (K)-specific methyltransferase 2D
- appl_detail:
- Immunohistochemistry: 1:50-1:200
- other_names:
- ALR; KMS; MLL2; MLL4; AAD10; KABUK1; TNRC21; CAGL114
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total KMT2D protein.
- Background:
- The protein encoded by this gene is a histone methyltransferase that methylates the Lys-4 position of histone H3. The encoded protein is part of a large protein complex called ASCOM, which has been shown to be a transcriptional regulator of the beta-globin and estrogen receptor genes. Mutations in this gene have been shown to be a cause of Kabuki syndrome.
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