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GJC2 Antibody

Catalog Number:

36810
other_names: Cx47; HLD2; GJA12; SPG44; CX46.6; LMPH1C; PMLDAR

Amount:

100μg
calculated_mw:
host_species: Rabbit

Price:

$319

Swiss-Prot No:

Swiss-Prot#: Q5T442
NCBI Gene ID: 57165
Gene Accssion: NP_065168

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide corresponding to residues near the C terminal of human gap junction protein, gamma 2, 47kDa

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total GJC2 protein.

Applications:

WB

Background:

This gene encodes a gap junction protein. Gap junction proteins are members of a large family of homologous connexins and comprise 4 transmembrane, 2 extracellular, and 3 cytoplasmic domains. This gene plays a key role in central myelination and is involved in peripheral myelination in humans. Defects in this gene are the cause of autosomal recessive Pelizaeus-Merzbacher-like disease-1.

References:

appl_detail:

Western blotting: 1:500-1:2000

Datasheet PDF

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