Product Datasheet
GJC2 Antibody
Catalog Number: 36810
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: Q5T442
NCBI Gene ID: 57165
Gene Accssion: NP_065168
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic peptide corresponding to residues near the C terminal of human gap junction protein, gamma 2, 47kDa
- appl_detail:
- Western blotting: 1:500-1:2000
- other_names:
- Cx47; HLD2; GJA12; SPG44; CX46.6; LMPH1C; PMLDAR
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total GJC2 protein.
- Background:
- This gene encodes a gap junction protein. Gap junction proteins are members of a large family of homologous connexins and comprise 4 transmembrane, 2 extracellular, and 3 cytoplasmic domains. This gene plays a key role in central myelination and is involved in peripheral myelination in humans. Defects in this gene are the cause of autosomal recessive Pelizaeus-Merzbacher-like disease-1.
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