PLCZ1 Antibody

Catalog Number:

36697

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: Q86YW0
NCBI Gene ID: 89869
Gene Accssion: BC125067/Q86YW0

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Fusion protein corresponding to residues near the C terminal of human phospholipase C, zeta 1

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total PLCZ1 protein.

Applications:

IHC

Background:

The protein encoded by this gene is a member of the phosphoinositide-specific phospholipase C family. Members in this family, classified into six isotypes that are tissue- and organ-specific, hydrolyze phosphatidylinositol 4,5-bisphosphate just before the phosphate group to yield diacylglycerol and inositol 1,4,5-trisphosphate. This protein localizes to the acrosome in spermatozoa and elicits Ca(2+) oscillations and egg activation during fertilization that leads to early embryonic development. Alternative splicing results in multiple transcript variants.?

References:

appl_detail:

Immunohistochemistry: 1:25-1:100

Datasheet PDF