Product Datasheet
PLCZ1 Antibody
Catalog Number: 36697
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: Q86YW0
NCBI Gene ID: 89869
Gene Accssion: BC125067/Q86YW0
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Fusion protein corresponding to residues near the C terminal of human phospholipase C, zeta 1
- appl_detail:
- Immunohistochemistry: 1:25-1:100
- other_names:
- PLCzeta; NYD-SP27; PLC-zeta-1
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total PLCZ1 protein.
- Background:
- The protein encoded by this gene is a member of the phosphoinositide-specific phospholipase C family. Members in this family, classified into six isotypes that are tissue- and organ-specific, hydrolyze phosphatidylinositol 4,5-bisphosphate just before the phosphate group to yield diacylglycerol and inositol 1,4,5-trisphosphate. This protein localizes to the acrosome in spermatozoa and elicits Ca(2+) oscillations and egg activation during fertilization that leads to early embryonic development. Alternative splicing results in multiple transcript variants.?
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