PABPC1 Antibody

Catalog Number:

36610

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: P11940
NCBI Gene ID: 26986
Gene Accssion: BC015958

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Fusion protein corresponding to a region derived from internal residues of human poly(A) binding protein, cytoplasmic 1

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total PABPC1 protein.

Applications:

WB

Background:

This gene encodes a poly(A) binding protein. The protein shuttles between the nucleus and cytoplasm and binds to the 3' poly(A) tail of eukaryotic messenger RNAs via RNA-recognition motifs. The binding of this protein to poly(A) promotes ribosome recruitment and translation initiation; it is also required for poly(A) shortening which is the first step in mRNA decay. The gene is part of a small gene family including three protein-coding genes and several pseudogenes.

References:

appl_detail:

Western blotting: 1:200-1:1000

Datasheet PDF