Product Datasheet
PABPC1 Antibody
Catalog Number: 36610
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: P11940
NCBI Gene ID: 26986
Gene Accssion: BC015958
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Fusion protein corresponding to a region derived from internal residues of human poly(A) binding protein, cytoplasmic 1
- appl_detail:
- Western blotting: 1:200-1:1000
- other_names:
- PAB1; PABP; PABP1; PABPC2; PABPL1
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total PABPC1 protein.
- Background:
- This gene encodes a poly(A) binding protein. The protein shuttles between the nucleus and cytoplasm and binds to the 3' poly(A) tail of eukaryotic messenger RNAs via RNA-recognition motifs. The binding of this protein to poly(A) promotes ribosome recruitment and translation initiation; it is also required for poly(A) shortening which is the first step in mRNA decay. The gene is part of a small gene family including three protein-coding genes and several pseudogenes.
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