LDOC1 Antibody

Catalog Number:

36583

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: O95751
NCBI Gene ID: 23641
Gene Accssion: BC003104

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Fusion protein corresponding to residues near the N terminal of human leucine zipper, down-regulated in cancer 1

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total LDOC1 protein.

Applications:

IHC

Background:

The protein encoded by this gene contains a leucine zipper-like motif and a proline-rich region that shares marked similarity with an SH3-binding domain. The protein localizes to the nucleus and is down-regulated in some cancer cell lines. It is thought to regulate the transcriptional response mediated by the nuclear factor kappa B (NF-kappaB). The gene has been proposed as a tumor suppressor gene whose protein product may have an important role in the development and/or progression of some cancers.

References:

appl_detail:

Immunohistochemistry: 1:50-1:200

Datasheet PDF