Product Datasheet  
LDOC1 Antibody  
Catalog Number: 36583  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot#: O95751
    NCBI Gene ID: 23641
    Gene Accssion: BC003104
  • Form of Antibody：  
  • Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • Fusion protein corresponding to residues near the N terminal of human leucine zipper, down-regulated in cancer 1
  • reactivity：  
  • Hu
  • appl_detail：  
  • Immunohistochemistry: 1:50-1:200
  • other_names：  
  • Mar7; BCUR1; Mart7
  • Purification：  
  • Antigen affinity purification.
  • Specificity：  
  • The antibody detects endogenous levels of total LDOC1 protein.
  • Applications：  
  • IHC
  • Background：  
  • The protein encoded by this gene contains a leucine zipper-like motif and a proline-rich region that shares marked similarity with an SH3-binding domain. The protein localizes to the nucleus and is down-regulated in some cancer cell lines. It is thought to regulate the transcriptional response mediated by the nuclear factor kappa B (NF-kappaB). The gene has been proposed as a tumor suppressor gene whose protein product may have an important role in the development and/or progression of some cancers.



 
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